Analysing Antibodies with Multi-Detector SEC Technology

Antibodies have generated a large amount of interest within the pharmaceutical industry, due in part to their ability to direct their own neutralisation attacks toward specific structures within harmful agents.

Since much of an antibody’s functionality depends on its molecular structure and integrity, full characterization, including molecular weight, size, and purity of these materials is critical to ensure efficacy

Size-exclusion chromatography (SEC), also referred to as gel permeation chromatography (GPC), is a widely used technique to characterise a range of samples, from bulk manufactured materials to proteins and other biological macromolecules, such as antibodies.

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